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Laguda B, Selden C, Jones M, Hodgson H, Spurr NK

The smaller studies that make up a meta-analysis can sometimes show larger effects than in a single study that has a lot more participants

While nicotine itself is not considered to be carcinogenic, each cigarette contains a mixture of carcinogens, including a small dose of polycyclic aromatic hydrocarbons (PAHs) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) among other lung carcinogens, tumor promoters, and co-carcinogens

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